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Home > What vitamins boost the immune system response best? > Vitamin D3
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Vitamin D3 (cholecalciferol) plays an important role in the functions of the immune system as well as well as its better known role in calcium balance (1). Its influence is on macrophages, and reduction of inflamed tissues. Shortages of Vitamin D inhibit immune system activity. Megadoses do not improve the immune system activity in people with a healthy immune system. So Vitamin D is involved in immune system regulation and helps the immune system of people with Vitamin D deficiency.
1. Maria S. Barnes, et. al., The Journal of Nutrition. Maintenance of Wintertime Vitamin D Status with Cholecalciferol Supplementation Is Not Associated with Alterations in Serum Cytokine Concentrations among Apparently Healthy Younger or Older Adults,1/26/2011, doi: 10.3945/jn.110.131516.
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